Innovative App-Based Program Promotes Diabetes Remission in India
Image Credit: Dr. Pramod Tripathi, CC-BY 4.0
Breakthrough in Diabetes Management
In a groundbreaking study published on October 22, 2025, in PLOS One, researchers led by Dr. Pramod Tripathi from the Freedom from Diabetes Clinic in India revealed that nearly 33% of participants with type 2 diabetes (T2D) achieved remission through a comprehensive lifestyle intervention. This study highlights the potential of lifestyle changes in managing diabetes, particularly in the Indian context where genetic predispositions and lifestyle factors increase risk.
Understanding the Indian Diabetes Challenge
India is home to over 72 million individuals living with type 2 diabetes. While lifestyle interventions have been effective in Western countries, their impact in India has been less explored. This study provides crucial insights into how tailored lifestyle programs can significantly improve health outcomes for the Indian population.
Study Design and Methodology
The research involved 2,384 adults with T2D who participated in a year-long online lifestyle intervention program from May 2021 to August 2023. The program, delivered via a mobile app, included a personalized plant-based diet, regular physical activity, group therapy, individual counseling, and medication management, all coordinated by a dedicated six-member care team.
Remarkable Results
Out of the total participants, 744 individuals (31.2%) achieved diabetes remission, defined as maintaining HbA1c levels below 48 mmol/mol for at least three months without the need for glucose-lowering medications. This group experienced more significant improvements in weight, BMI, HbA1c, fasting insulin, and insulin resistance compared to those who did not achieve remission.
Key Predictors of Success
Participants under 50 years of age, with higher BMI, no prior medication use, and a shorter duration of diabetes were more likely to achieve remission. These findings underscore the importance of early intervention and personalized care in diabetes management.
Implications for Future Research
This study opens new avenues for diabetes treatment strategies, emphasizing the role of lifestyle modifications. It also calls for further research to explore the long-term sustainability of such interventions and their applicability to other populations.
Global Relevance
While the study focuses on an Indian cohort, its implications are global. As diabetes continues to rise worldwide, understanding effective management strategies is crucial. This research contributes valuable knowledge to the global fight against diabetes.
Challenges and Considerations
Implementing such intensive programs on a larger scale presents challenges, including resource allocation and ensuring participant adherence. However, the potential health benefits make it a worthwhile endeavor.
Conclusion
The success of this app-based lifestyle intervention program in achieving diabetes remission highlights the transformative power of technology and personalized care. It offers hope to millions battling diabetes and sets a precedent for future health interventions.
About the Study
Authors: Pramod Tripathi, Nikhil Kadam, Tushar Kathrikolly, Deepak Tiwari, Anjali Vyawahare, Bhavna Sharma, et al.
Funding: No specific funding was received for this study.
Journal: PLOS One
DOI: 10.1371/journal.pone.0333114
Method of Research: Observational study
Subject of Research: People
Article Title: Type 2 diabetes remission and its predictors in an Indian cohort: A retrospective analysis of an intensive lifestyle intervention program
News Publication Date: 22-Oct-2025
Image Credits: Dr. Pramod Tripathi, CC-BY 4.0
Keywords
Tags: diabetes management in India, diabetes research foundation, effective diabetes treatment strategies, Freedom from Diabetes Clinic, health technology for diabetes, Indian diabetes cohort study, intensive app-based lifestyle program, lifestyle changes for diabetes, lifestyle intervention programs, PLOS One diabetes research, predictors of diabetes remission, Type 2 diabetes remission
